How to Use RESTASIS® Ophthalmic Emulsion

You have been prescribed RESTASIS® Ophthalmic Emulsion, a prescription therapy for dry eye patients clinically shown to increase production of one’s own natural tears. RESTASIS® Ophthalmic Emulsion is both an artificial tear which treats your symptoms for short term relief of persistent dry eye and a special medicine which works, with proper compliance, to increase both quantity and quality of your own natural tear production in the long term. RESTASIS® Ophthalmic Emulsion can actually help you restore the production of your own natural tears – something that an artificial tear alone cannot do by itself.

You may choose to continue using artificial tears between doses of RESTASIS® for temporary relief of your dry eye symptoms. Over time, however, you may find that you need these less often, if at all.

RESTASIS® should be used as follows:
1 drop in each eye, 2 times per day, 12 hours apart.
“A vial a day, then throw it away”

What you should expect with RESTASIS® therapy:


  • 0 – 6 weeks: it is typical to note some improvement in signs and symptoms such as dryness, itching, blurred vision late in the day and sensitivity to light. Not all patients respond as quickly as others and proper compliance with twice a day dosing is critical to resolution of dry eye symptoms. Improvement can also be dependent upon the severity of your dry eye disease or dysfunctional tear syndrome. DO NOT DISCONTINUE USE WITHOUT CONSULTING YOUR DOCTOR!
  • 6 weeks – 3 months: key signs and symptoms will continue to improve with less reliance on artificial tears.
  • 3 – 6 months: improvement of symptoms and clinical signs maintained with continued therapy.


You may experience a stinging sensation when instilling RESTASIS®. This is common in 1 out of 6 patients. This should go away with continued use over time. Refrigerating your RESTASIS® or using artificial tears 15 minutes before RESTASIS® may ease this temporary discomfort.

My Tears, My RewardsPlease visit for a $20 rebate check offer and sign up for the My Tears, My Rewards program to access additional savings and information. Membership is free at RESTASIS® Customer Support Center can be reached at 1-866-572-5931 for any additional concerns or questions.